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非酒精性脂肪性肝病(NAFLD)包括从单纯脂肪变性到非酒精性脂肪性肝炎(NASH)等不同严重程度的肝脏病变,而NASH可发展为肝硬化并最终发展为肝细胞癌,是当前全球肝移植和肝脏相关死亡率的主要因素之一。然而,目前还没有药物被批准用于非酒精性脂肪肝的临床治疗。肝脏中脂肪酸从头合成(DNL)速率的增加是非酒精性脂肪性肝病的一个显著特征。先前的研究表明,抑制脂肪酸从头合成中的限速酶乙酰辅酶a羧化酶(AC...
Background: Pertussis or “whooping cough” is an acute, communicable infection of the respiratory tract caused by the Gram-negative bacterium Bordetella pertussis. It has been recorded in history of me...
A SRY-negative XX male describes a female karyotype with testicular tissue resulting from abnormal gonadal development. In such cases male gonad formation takes place in the absence of a Y chromosome ...
Introduction: Superior mesenteric artery syndrome is an uncommon cause of duodenal obstruction, and its manifestations are generally associated with compression on the third part of the duodenum betwe...
Introduction: Pyometra is an accumulation of purulent material or pus in the uterine cavity. Spontaneous perforation of uterus by pyometra is rare. This is a clinical presentation and management of a ...
Introduction:: Tumors which originate from the Bartholin’s glands (BGs) are very rare. Many solid masses that arise from the BGs are carcinoma, though these benign solid lesions are rare.
Introduction:: The use of traditional medicine has been emerged in the treatment of BPS (bladder pain syndrome) due to its high prevalence and expenses and its insufficient treatment by conventional t...
Introduction:: Wart is a contagious dermal disease with different types. Wart has long-term treatment with symptoms of multiple relapses, which involve larger surfaces. It has no definite medical trea...
Sleep and circadian timing are fundamental biological imperatives in animals and humans, throughout the lifespan. These biological systems can be challenged by pathology, individual choices, and so...
Background: Zoonotic Cutaneous Leishmaniasis (ZCL) is an endemic health problem in many rural areas of Iran, with doubled number of incidences over the last decade. Different species of rodents serve ...
Extramedullary plasmacytoma is a rare neoplasm characterized by monoclonal proliferation of plasma cells. Most lesions occur in the head and neck, primarily in the upper aerodigestive tract. The nasal...
Introduction: With the introduction of a new curriculum “Modellstudiengang Medizin” in Aachen, the education in medical psychology was also restructured. This paper presents data from the students’ ev...
With the introduction of a new curriculum “Modellstudiengang Medizin” in Aachen, the education in medical psychology was also restructured. This paper presents data from the students’ evaluations of t...
Post-transplant lymphoproliferative disorder is a lymphocyte proliferating disease, usually of B cell origin, and rarely of T cell. Involvement of liver itself in liver transplant recipients as the pr...

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